DNA VARIANT TYPING
HUGE-F provides a variety of options for researchers who are considering genotyping or variant typing projects. Depending on the specific project, we provide solutions requiring services aimed at determining a low to mid-plexity of SNPs over many samples to SNP discovery on a genome-wide level. Scientific goals may overlap across platforms, and we therefore encourage our customers to contact us at an early stage to discuss the details of their project.
We offer variant typing options for:
-- telomere length
-- mitochondrial copy number
-- diagnostic purposes (according to ISO methods)
The diverse platforms available for genotyping include:
-- Agena Bioscience iPLEX
-- ABI GeneMapper
-- Illumina Infinium SNP array technology
-- Thermofisher Scientific / Affymetrix SNP array technology
-- custom iSelect
-- SNP and CNV analysis using Illumina next-generation sequencing
-- Custom panels are also available for several platforms
Infinium Global®Screening Array from Ilumina
We offer DNA genotyping using the Infinium® Global Screening Array (GSA). This Illumina array has a very rich up-to-date content and is suitable for GWAS including rare variants, while also containing clinically relevant content.
Axiom™ Precision Medicine Arrays from ThermoFisher Scientific / Affymetrix
Axiom Precision Medicine Diversity Array (PMDA) Axiom Precision Medicine Research Array (PMRA) are comprehensive imputation-aware genotyping resources each offering >900K variants enabling insights into complex disease susceptibility, immune response, pharmacogenomics research among others. Arrays offer large GWAS grid (>800K markers) to boost disease association studies across diverse populations inclusive of EUR.